What was the primary strategic goal of NASA's HOPE study concerning a Callisto surface base?

Answer

In-situ production of rocket propellant.

The primary strategic goal for the proposed Callisto outpost in the HOPE study was the in-situ production of rocket propellant from the moon's abundant water ice, making it a crucial supply depot.

What was the primary strategic goal of NASA's HOPE study concerning a Callisto surface base?
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