What is the primary mechanism responsible for creating naturally occurring, very heavy elements like uranium?

Answer

The r-process (Rapid Neutron Capture)

The r-process involves atomic nuclei being bombarded so rapidly by a flux of free neutrons during the explosive core collapse and rebound that they capture many neutrons before they have time to undergo radioactive beta decay, thus creating the heaviest elements.

What is the primary mechanism responsible for creating naturally occurring, very heavy elements like uranium?

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