How does the density of a typical nebula compare to the best laboratory vacuum achievable on Earth?

Answer

It is far less dense than the best laboratory vacuum.

Although nebulae are described as vast interstellar clouds where matter is highly concentrated relative to the near-vacuum between galaxies, this concentration is still incredibly diffuse when compared to terrestrial standards. A typical nebula might only contain a few hundred atoms per cubic centimeter. This concentration is significantly lower than what can be achieved in the best laboratory vacuums created on Earth. While this relative concentration within the nebula allows astronomers to observe structure and processes, the overall environment is almost a perfect vacuum by everyday standards, being many orders of magnitude less dense than the best man-made vacuums.

How does the density of a typical nebula compare to the best laboratory vacuum achievable on Earth?
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