What is the primary hazard associated with the cascade effect of an Ultra-High-Energy Cosmic Ray (UHECR) hitting tissue?

Answer

Acute cellular death in a small region due to dense ionization along the path

The cascade effect produces a dense 'tree' of secondary particles that deposits a massive, localized amount of energy, causing acute cellular death in the very small volume it traverses.

What is the primary hazard associated with the cascade effect of an Ultra-High-Energy Cosmic Ray (UHECR) hitting tissue?

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Why Are Cosmic Rays Dangerous? | How The Universe Works

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