What is the primary long-term strategy proposed for enabling sustainable, powerful space exploration?

Answer

In-Situ Propellant Production ($ ext{ISRU}$) using local off-world resources.

ISRU involves manufacturing propellant, such as producing $ ext{LOX}/ ext{LH}_2$ from lunar water ice or synthesizing methane on Mars, which shifts the logistical burden away from launching all reaction mass from Earth.

What is the primary long-term strategy proposed for enabling sustainable, powerful space exploration?

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