Which rocket is the only family to successfully transport humans beyond low Earth orbit?

Saturn V

The Saturn V rocket holds the unique distinction in history as being the only rocket family ever documented to have transported human crews beyond the boundaries of low Earth orbit. This monumental capability was demonstrated repeatedly during the Apollo program when it successfully propelled astronauts all the way to the lunar surface. Furthermore, even after the Moon landings concluded, the Saturn V was utilized as the heavy-lift launch vehicle for the Skylab space station, further cementing its legacy as the ultimate deep-space powerhouse of its era. Its design prioritized sheer brute force necessary to escape Earth's gravitational influence for ambitious interplanetary trajectories, a feat matched by subsequent vehicles only in capability for deep space objectives, but not in having carried humans beyond LEO.