What was the total number of missions conducted by the entire Space Shuttle fleet from 1981 to 2011?
Answer
135 missions
Across its lifespan, the Space Transportation System (STS) era saw the fleet conduct a combined total of 135 orbital missions.

Related Questions
Which Space Shuttle orbiter accumulated the highest number of orbital journeys?What was the total number of missions conducted by the entire Space Shuttle fleet from 1981 to 2011?How many orbital flights did Space Shuttle *Atlantis* complete?How many flights had *Challenger* flown before it was lost in 1986?Which orbiter was the first to fly the Spacelab science module?Which orbiter was built specifically to replace *Challenger* in the fleet?Which shuttle was responsible for flying the first assembly mission (STS-88) to connect the U.S. and Russian ISS modules?What key role did *Discovery* play immediately following the *Challenger* disaster?Which orbiter performed the first servicing mission (STS-61) for the Hubble Space Telescope?What primary focus did the shuttle manifest shift to after the *Columbia* accident (post-STS-107)?Where was Space Shuttle *Atlantis* placed on display after its retirement?